While the Fox Network has yet to deliver on premiere dates for new and returning shows this fall, we can tell you that soapy medical drama series Doc has locked in on a premiere date for Season 2.

The show will officially return Tuesday, Sept. 23, 2025 with the first episode in a new 22-episode expanded season.

Doc follows Dr. Amy Larsen (Molly Parker), the brilliant but emotionally cold Chief of Internal Medicine at Westside Hospital. When Amy suffers a catastrophic brain injury, her life is turned upside down. With key negative events expunged from her mind Amy charts a path forward, determined to once again practice medicine, but in a kinder, gentler way. However, for her colleagues, her family, and her ex-husband, the new Amy is a person they are reluctant to trust, particularly when her memories begin to come trickling back.

Season 2 of the gentle melodrama sees Felicity Huffman (Desperate Housewives, Sports Night) joining the cast as Dr. Joan Ridley, Amy’s med school professor and early mentor.

Fox teases that their dynamic will be layered, charged, and deeply rooted in mutual respect, with just enough friction to keep it honest, prompting Michael (Omar Metwally) to offer her the open Chief of Internal Medicine job at Westside, succeeding Dr. Richard Miller (Scott Poter). While it’s true that she’s here to help Amy, and the rest of the department, she also has a secret that’s motivating her even more.

In additional casting news, Patrick Walker (Dr. Theodore “T.J.” Coleman) and Charlotte Fountain-Jardim (Katie Hamda, Amay’s daughter) have both been promoted to series regulars.

This season Fox is pairing Doc with procedural whodunit Murder in a Small Town on Tuesday nights. It’s likely the Rossif Sutherland and Kristin Kreuk-starring series, based on the Alberg and Cassandra Mysteries (a series of B.C.-set crime novels by author L. R. Wright), will also return on Sept. 23, 2025.

More as we have it.

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