BEST MEDICINE HAS BEEN RENEWED FOR A 12-EPISODE SECOND SEASON

Episode 1×13 “Norway No How”

SEASON FINALE

SYNOPSIS: As the furious people of Port Wenn discover the truth about their deal with their Norwegian sister city, Martin must toggle between the potential revelation of his blood phobia, a startling baby delivery and the arrival of his amorous ex, Dr. Eden Montgomery (Eliza Coupe).

Also, Louisa receives some thought-provoking medical results and Al and Elaine must navigate their uncertain future.

AIR DATE: Tuesday, Apr 7 8:00-9:00 PM ET/PT on FOX.

PHOTOS: “Norway, No How”

Episode 1×12 “A Tale of Two Sister Cities”

SYNOPSIS: Martin is skeptical when Port Wenn welcomes an extremely friendly delegation from their sister city in Norway and Louisa visits a specialist who just happens to be Martin’s ex.

Also, Greg believes that he is pooping little men and Mark exhibits troubling symptoms that warrant an intervention.

AIR DATE: Tuesday, Mar 31 8:00-9:00 PM ET/PT on FOX.

PHOTOS: “A Tale of Two Sister Cities”

Episode 1×11 “Mind Your Own Buboes

SYNOPSIS: Port Wenn goes on lockdown when a patient with fleas sparks fears of a plague outbreak and Martin must deal with the town gossip when it revolves around him and Louisa.

Also, Aunt Sarah feels betrayed by Greg and George and Louisa has an epiphany.

AIR DATE: Tuesday, Mar 24 8:00-9:00 PM ET/PT on FOX.

PHOTOS: “Mind Your Own Buboes”

Episode 1×10 “Port Wenn-ings and a Funeral”

SYNOPSIS: After Martin invites Louisa to watch the annual bird migration over Port Wenn, he treats an elderly woman whose hallucinations lead to dire consequences.

Meanwhile, Aunt Sarah fumes after the reading of a will leaves her nothing and Martin must perform an emergency procedure on his young friend.

AIR DATE: Tuesday, Mar 10 8:00-9:00 PM ET/PT on FOX.

PHOTOS: “Port Wenn-ings and a Funeral”

Episode 1×09 “Doc Martin”

SYNOPSIS: When Martin’s parents make a surprise visit, Martin suspects that his father, Robert, blindsides his sister Sarah with some infuriating news, is experiencing a serious health condition.

Also, while trying to avoid the school’s forthcoming closure amidst its annual Spirit Week sleepover, Louisa is made acting principal and Martin and Robert must operate together on Mark.

AIR DATE: Tuesday, Mar 3 8:00-9:00 PM ET/PT on FOX. 

PHOTOS: “Doc Martin”

Episode 1×08 “The Bog Father”

SYNOPSIS: Sensing high drama and mystery, Port Wenn eagerly goes into high alert when a corpse is found in the town’s bog and Martin’s autopsy reveals that he was murdered.

Meanwhile, Martin’s solo investigation trek leads him to startling discovery about himself and the new neighborhood watch turns into a gossip-seeking mission.

AIR DATE: Tuesday, Feb 24 8:00-9:00 PM ET/PT on FOX.

PHOTOS: “The Bog Father”

Episode 1×07 “There Might Be Blood”

SYNOPSIS: When Port Wenn puts on their annual ‘Blood Factory,’ celebrating the gory horror novel set there, Martin must contain his secret debilitating blood phobia when Louisa gets seriously ill and needs his help.

Meanwhile, the town is all atwitter when the novel’s author is rumored to be making a surprise visit to the event.

AIR DATE: Tuesday, Feb 17 8:00-9:00 PM ET/PT on FOX.

PHOTOS: “There Might be Blood”

Episode 1×06 “Eyewitness Blues”

SYNOPSIS: On the eve of Port Wenn’s annual blueberry festival, Martin treats a local man who has apparently become blue from eating too many blueberries.

Also, Martin is disturbed by Aunt Sarah’s lack of attention to her health.

Meanwhile, Mark faces the repercussions when he learns his vision issues may stem from his sexual history, and Louisa is determined to win the pie competition.

AIR DATE: Tuesday, Feb 10 8:00-9:00 PM ET/PT on FOX. 

PHOTOS: “Eyewitness Blues”

Episode 1×05 “Hello Darkness My Port Wenn”

SYNOPSIS: While conducting a wellness check on the agoraphobic recluse who controls the town power grid and has stopped taking his meds, Martin’s brusque bedside manner ultimately causes a massive town black out.

As the townspeople fight for electricity, Martin befriends a young boy who reminds him of himself and Louisa and Mark share a romantic moment in the dark.

AIR DATE: Tuesday, Feb 3 8:00-9:00 PM ET/PT on FOX.

PHOTOS: “Hello Darkness My Port Wenn”

Episode 1×04 “All the World’s Ablaze”

SYNOPSIS: Port Wenn’s favorite hunky wilderness survival instructor goes missing after Martin deduces that he desperately needs medical help.

Also, the locals are furious with Martin after he calls the health inspector on The Salty Breeze suspecting food poisoning and Elaine decides to skip her mother’s wedding to the school principal.

AIR DATE: Tuesday, Jan 27 8:00-9:00 PM ET/PT on FOX.

PHOTOS: “All the World’s Ablaze”

Episode 1×03 “Take Me Out to the Ballgame”

SYNOPSIS: On the eve of Port Wenn High School’s baseball team’s playoff game, the town is furious with Martin when he accidentally breaks the arm of their star player, who happens to be the son of his high school bully.

However, Martin suspects the boy has a more serious condition.

Meanwhile, Elaine moves into Martin’s waiting room after fighting with her mom, Aunt Sarah rivals with a fan of the opposing team, and Louisa makes a conscious effort to make some female friends.

AIR DATE: Tuesday, January, 20 7:00-8:00 PM ET/PT on FOX.

PHOTOS: “Take Me Out to the Ballgame”

Episode 1×02 “Bean There, Done That”

SYNOPSIS: After Martin comes face to face with his childhood bully and diagnoses a potentially contagious illness, he is forced to cancel Port Wenn’s monthly baked bean supper, angering everyone in the town.

Also, Louisa observes Mark getting friendly with her teaching assistant, while Elaine steps in to help Martin in an unexpected, but very much needed, way

AIR DATE: Tuesday, Jan 13 7:00-8:00 PM ET/PT on FOX.

PHOTOS: “Bean There, Done That”

Episode 1×01 “Docked”

SERIES PREMIERE

SYNOPSIS: Brilliant and brusque renowned surgeon Martin Best leaves his lucrative career in Boston to become the general practitioner in the small seaside village of Port Wenn, Maine.

One local teacher, Louisa Gavin questions his harsh demeanor, while Martin quickly gets annoyed by the antics of its town locals, all while hiding his debilitating aversion to blood.

SPECIAL AIR DATE: Sunday, Jan. 4 (8:00-9:00 PM ET / Live to All Time Zones) immediately following the FOX NFL doubleheader. Best Medicine will have it’s time period premiere on Tuesday, Jan 6 (8:00-9:00 PM ET/PT) on FOX. 

ABOUT BEST MEDICINE

Best Medicine joins FOX’s Primetime lineup Mid-Season in 2026.

Starring Josh Charles (The Handmaid’s Tale, The Good Wife), Best Medicine is described as a “charmingly complicated” one-hour comedy based on the British hit series Doc Martin, originally starring Martin Clunes.  

The series centers on Martin Best (Charles), a brilliant surgeon who abruptly leaves his illustrious career in Boston to become the general practitioner in a quaint East Coast fishing village where he spent summers as a child.

Unfortunately, Martin’s blunt and borderline rude bedside manner rubs the quirky, needy locals the wrong way, and he quickly alienates the town, even though he’s all they’ve got.

Although Martin can expertly address any medical ailment or mystery in this idiosyncratic town, he’s really just desperate to be left the hell alone. Instead, he keeps getting dragged right smack into the middle of their personal chaos, feuds and fantasies.

What the locals don’t know is that Martin’s terse demeanor masks a debilitating new phobia and deep-seated psychological issues that prevent him from experiencing true intimacy with anyone.

But tenacity is the creed of everyone in their small village, and the people who live there may be exactly what the doctor ordered.

Wholly owned by FOX Entertainment, Best Medicine is from executive producers Ben Silverman (The Office, U.S.), Rodney Ferrell (Stick), Howard T. Owens (Stick), Liz Tuccillo (Sex and the City), Mark Crowdy (Doc Martin) and Philippa Braithwaite (Doc Martin).