FOX is the third of the ‘Big 4’ Networks to reveal its slate for 2025. Compared to CBS, which has added to its franchises again this year, and NBC who has decided to forego any new dramas in favor of more sports programming, FOX has two new series in the offing this fall.
Airing this fall alongside Doc (renewed for a full 22 episode season season earlier this year), and Murder in a Small Town (also returning for Season 2), is Memory of a Killer, a thriller starring Grey’s Anatomy alum Patrick Dempsey about a hitman who develops early onset Alzheimer’s. Fall will also see the debut of new comedy drama Best Medicine, starring Josh Charles, and based on the series Doc Martin.
The Network also plans The Faithful, a 6 episode biblical mini-series.
Meanwhile, comedies American Dad!, Animal Control, Best Medicine, Bob’s Burgers, Family Guy, Going Dutch, Grimsburg, Krapopolis, Universal Basic Guys and The Simpsons have all been renewed ahead of the new season.
The Cleaning Lady (currently airing its fourth season) and Alert: Missing Persons Unit (airing its third) are both of unknown renewal status at this time.
More as we have it. Catch the full schedule below and follow us @TVPulseMag on X and TVPulseMag.com on Bluesky for more TV news.
FOX FALL 2025 SCHEDULE
(All Times ET/PT)
MONDAY
8:00-9:00 PM Name That Tune
9:00-10:00 PM Celebrity Weakest Link (new series)
TUESDAY
8:00-9:00 PM Murder In a Small Town
9:00-10:00 PM Doc
WEDNESDAY
8:00-9:00 PM The Floor
9:00-10:00 PM 99 To Beat (new unscripted series)
THURSDAY
8:00-9:00 PM Hell’s Kitchen
9:00-10:00 PM Special Forces: World’s Toughest Test
FRIDAY
8:00 PM-CC ET/ FOX College Football Friday
5:00 PM-CC PT
SATURDAY
7:00-10:30 PM ET/ Fox Sports Saturday
4:00-7:30 PM PT
SUNDAY
7:00-7:30 PM NFL On Fox
7:30-8:00 PM The OT / FOX Animation Encores
8:00-8:30 PM The Simpsons
8:30-9:00 PM Universal Basic Guys
9:00-9:30 PM Krapopolis
ABOUT MEMORY OF A KILLER
Inspired by the 2003 Belgian film De Zaak Alzheimer (La Memoire Du Tueur), Memory of a Killer is a thriller about a hitman who develops early onset Alzheimer’s.
Losing your memory is a devastating hammer blow for anyone, but for Angelo Ledda, the stakes couldn’t be higher. His hit man job would be perilous enough, but there’s an added pressure. Angelo lives two totally separate lives — fearsome NYC hitman and sleepy upstate Cooperstown photocopier salesman and father. Having built and maintained a brick wall between his two worlds, Angelo has seamlessly juggled and compartmentalized for years. But now that’s all about to change. Because Alzheimer’s is a foe he can’t outrun, and he knows too well how this ends, as his older brother is already lost to the condition.
Angelo is exceptionally resourceful and talented, the best of the best. But he’s about to be tested like never before — and now every minute counts. This is only made more difficult when he discovers that his wife’s recent death may not have been an accident. So, when someone comes after his daughter — who is pregnant — it’s clear the wall between his lives has been breached. Angelo must stop whoever’s coming for his family by searching his past hits for clues, and the list is very long. Now Angelo must hunt down his mortal enemy while continuing to carry out hits without giving away his diagnosis and still making it home in time to cook dinner for his daughter.
FOX describes the new drama as a “redemptive story about a man who is losing his memory but gaining a conscience.”
Because Angelo knows he must stop history from repeating itself and save his family — before he forgets the past.
Memory of a Killer is produced by Warner Bros. Television and FOX Entertainment. The series is from Ed Whitmore and Tracey Malone, who executive produce alongside Cathy Schulman of Welle Entertainment.
ABOUT BEST MEDICINE
Starring Josh Charles (The Handmaid’s Tale, The Good Wife, Sports Night, Dead Poets Society), Best Medicine is described as a “charmingly complicated” one-hour comedy based on the British hit series Doc Martin, originally starring Martin Clunes.
The series centers on Martin Best (Charles), a brilliant surgeon who abruptly leaves his illustrious career in Boston to become the general practitioner in a quaint East Coast fishing village where he spent summers as a child. Unfortunately, Martin’s blunt and borderline rude bedside manner rubs the quirky, needy locals the wrong way, and he quickly alienates the town, even though he’s all they’ve got.
Although Martin can expertly address any medical ailment or mystery in this idiosyncratic town, he’s really just desperate to be left the hell alone. Instead, he keeps getting dragged right smack into the middle of their personal chaos, feuds and fantasies.
What the locals don’t know is that Martin’s terse demeanor masks a debilitating new phobia and deep-seated psychological issues that prevent him from experiencing true intimacy with anyone.
But tenacity is the creed of everyone in their small village, and the people who live there may be exactly what the doctor ordered.
Wholly owned by FOX Entertainment, Best Medicine is from executive producers Ben Silverman (The Office, U.S.), Rodney Ferrell (Stick), Howard T. Owens (Stick), Liz Tuccillo (Sex and the City), Mark Crowdy (Doc Martin) and Philippa Braithwaite (Doc Martin).
